Solve what’s been unsolvable in clinical trials - redefining what’s achievable!

Ask CoTrial AI

Candidate Identification

Can you identify the best candidates for this trial using cohort-level embeddings that model completion likelihood rather than static eligibility — and show the forecasted survival dynamics, adherence indicators, and site-level operational factors contributing to each composite ranking score?

AE Forecasting

Can you forecast which participants are most likely to experience Grade ≥3 adverse events in the next 21 days by integrating lab trends, dosing history, and AE narratives — and explain how the model distinguishes true drug toxicity from comorbidity or site-related noise?

Compliance & Regulatory Automation

Can you automatically generate a 21 CFR Part 11–compliant audit packet for this analysis — including model lineage, retrieval context, and decision traceability — without exposing PHI or requiring manual documentation review?

CoTrial AI outperforms the following AI Models

TrialGPT, Panacea, TrialMatchAI, MatchMiner-AI, LLM-Match, DeepEnroll, OTESSA and PRISM, etc..

Feature / Capability CoTrial AI Eligibility AI ToolsDeep 6 AI, Deep Lens Ops / Analytics PlatformsMedidata, TriNetX, ConcertAI Generic AI ModelsOpenAI, Anthropic
Core GoalMulti-agent orchestration across Candidate Selection, AE Forecasting, and Compliance; uses hybrid reasoning + numerical modelingText mining of EHR for eligibility, Site/patient
pre-screening		Portfolio-level analytics + dashboardsGeneral AI APIs, not designed for trials
Probabilistic eligibility P(eligible)YesNoNoNo
Completion likelihood (survival; calibrated)YesNoLimitedNo
Early AE forecastYesNoNo
Counterfactual policy sim (CrCl, arm switch)YesNoOps-level OnlyNo
Per-subject audit
packet (decision
DAG)		YesLimitedSystem-AuditNo
Site-level priors & friction indexYesPartialNoNo
Cross-trial priors (trial graph)Yes (Privacy-preserving)LocalNetwork AggregatesNo
Part 11 evidence kit (prompts, retrievals, versions)YesNoNoNo

CoTrial Screening

Machine-executable logic graphs, fusing LLM-RAG reasoning, DeepSurv survival modeling, and behavioral transformers to rank candidates by completion probability — not just eligibility.

CoTrial AE Forecasting

An AI time-series forecasting models multi-modal streams — labs, vitals, dosing, AE narratives — to detect Grade ≥3 toxicity up to 21 days before onset.

CoTrial Compliance

Every AI decision generates a versioned Decision DAG with model IDs, retrieval logs, and audit lineage, automatically producing 21 CFR Part 11–compliant evidence packets.

Built for CROs, Trial Sites, Drug Developers, Pharmaceutical Labs, Research Institutes etc..

Savings for Pharma = $5M–$10M per trial; cost of using CoTrial AI agent = < 1% of savings.

Ask CoTrial AI 24/7

Our AI Assistant ingests and analyzes all clinical trial files, extracting insights, trends, and issues to help hospitals, insurers, and researchers quickly understand data and make smarter decisions—while providing 24/7 chat support for real-time answers.

Unstructured Data File Ingestion

Our AI supports multi-format file ingestion, efficiently parsing diverse clinical trial documents—PDFs, spreadsheets, images, and proprietary formats—for comprehensive and accurate data extraction.

HIPAA & GDPR Compliance, Built In

CoTrial AI is HIPAA and GDPR compliant from day one, running on secure cloud infrastructure with built-in consent tracking, access control, data minimization, and PHI redaction with audit trails to ensure privacy and trust.

AI Knowledge Vault, Team Collaboration

Our knowledge vault centralizes clinical trial insights, enabling teams to securely share files, ask questions, and collaborate—turning data into actionable, shared knowledge.

Empower Your Team With CoTrial AI

On avg, CoTrial saves $150K–$250K in staff cost per trial → again ROI is massive (50–100x)

CoTrial Docs 2.5

$2.1 / 1M Input tokens Popular

Our state-of-the-art embedding model designed for precise retrieval across noisy, multilingual, and multimodal data.

For institutions with large database

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MOST POPULAR

CoTrial Inquiry 3.0

$2.00 / 100 Inquiries

Our AI search foundation model for enhancing the relevance of information surfaced within search and RAG systems.

For day to day healthcare professionals

  • Answers complex, document-grounded questions across protocols, CSRs, ICFs, and SAPs.
  • Understands and accurately responds to GCP, FDA 21 CFR Part 11, ICH E6(R3), and EMA guidance-related questions.
  • Supports questions requiring multiple sources: protocol + SAP, or ICF + CSR.
  • Understands conversational context across follow-up questions.
  • Adapted to sponsor SOPs, terminology, and therapeutic areas (e.g., oncology, cardiology, CNS).
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Clario
Veeva Oracle Analytics

Integration

Seamless AI Agent Integration Across CTMS (Clinical Trial Management Systems), EDC, eTMF, RWEs (Real-World Evidence), etc.